Currently it is not possible to trigger a Layout Zone with Lua. An example: click a button to take a token out of a bag, move it to a LZ, and then lay it on a grid.
You can put Scripting Zone with the same size over the Layout Zone.
True, but the issue is triggering the layout with script. AFAIK the only way to trigger layouts is either through the context menu or by picking up and dropping an object in the Zone.